The effects of testosterone on the physiological response to social and somatic stressors.

In this study, we addressed the role of the hormone testosterone in stress response using a single-dose administration to healthy volunteers. We found that testosterone’s effects were dependent on the type of stressor: testosterone increased activation of the sympathetic autonomic nervous system to a somatic stressor, but decreased its activation elicited by a social stressor. Thus, in response to different types of challenge, testosterone can adaptively up- or down-regulate the stress response to deal with the particular demands of the situation.
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