Centre of Experimental Medicine, Slovak Academy of Sciences


The Institute of Normal and Pathological Physiology (INPP) is involved in basic research in experimental medicine, in particular normal and pathological physiology with the focus on the cardiovascular and the nervous system. A special attention is paid to hypertension and circulation disorders, the structure of the cardiovascular system, social stress, brain information processing, the mechanisms of posture and balance control, as well as modelling of the processes in the nervous and cardiovascular systems. The institute has an established collaboration with several research institutions and clinical departments in Slovakia and abroad.
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Brain stimulation revealed new knowledge on semantic memory

Semantic control system regulates retrieval of knowledge according to current needs. We studied the brain mechanisms of this system using non-invasive transcranial direct current stimulation (tDCS) and found that stimulation of the left lateral prefrontal cortex improved inhibition of pre-potent semantic associations but not retrieval of habitual associations or switching between retrieval rules. Our findings […]

The effects of testosterone on the physiological response to social and somatic stressors.

In this study, we addressed the role of the hormone testosterone in stress response using a single-dose administration to healthy volunteers. We found that testosterone’s effects were dependent on the type of stressor: testosterone increased activation of the sympathetic autonomic nervous system to a somatic stressor, but decreased its activation elicited by a social stressor. […]

Natural Psychoplastogens As Antidepressant Agents

Our colleagues Jakub Benko and Stanislava Vrankova published a review “Natural Psychoplastogens As Antidepressant Agents“. In it they summarise the up to date research on this newly defined drug class. The definition was put forward by Olson and colleagues based on a couple of research articles. They observed that several previously unrelated classes of drugs […]